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Article

Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss.

Obesity (Silver Spring, Md.) - 1 Aug 2008

Haupt Axel, Thamer Claus, Machann Jürgen, Kirchhoff Kerstin, Stefan Norbert, Tschritter Otto, Machicao Fausto, Schick Fritz, Häring Hans-Ulrich, Fritsche Andreas

Abstract excerpt

Polymorphisms in the fat mass- and obesity-associated (FTO) gene have been identified to be associated with obesity and diabetes in large genome-wide association studies. We hypothesized that variation in the FTO gene has an impact on whole body fat distribution and insulin sensitivity, and influ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18535549
DOI: 10.1038/oby.2008.283

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18535549-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss.PMID 18535549Read ↗

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.Semantic proximity Read ↗

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FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.Semantic proximity Read ↗

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Variation in the FTO gene influences food intake but not energy expenditure.Semantic proximity Read ↗

FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness.Semantic proximity Read ↗

Impact of fat mass and obesity-associated (FTO) gene variants on adult obesity and overweight: a comprehensive meta-analysis.Semantic proximity Read ↗

FTO genotype is associated with exercise training-induced changes in body composition.Semantic proximity Read ↗

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.Semantic proximity Read ↗

FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women.Semantic proximity Read ↗

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Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.Semantic proximity Read ↗

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