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Article

Protective effect of the T112 PrP variant in sheep challenged with bovine spongiform encephalopathy.

The Journal of general virology - 1 Oct 2009

Saunders G C, Lantier I, Cawthraw S, Berthon P, Moore S J, Arnold M E, Windl O, Simmons M M, Andréoletti O, Bellworthy S, Lantier F

Abstract excerpt

Sheep with an ARQ/ARQ PRNP genotype at codon positions 136/154/171 are highly susceptible to experimental infection with bovine spongiform encephalopathy (BSE). However, a number of sheep challenged orally or intracerebrally with BSE were clinically asymptomatic and found to survive or were diagnosed as BSE-negative when culled. Sequencing of the full PRNP gene open reading frame of BSE-susceptible and -resistant...

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Share to Encephalopathy, Bovine Spongiform

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19587133
DOI: 10.1099/vir.0.012724-0

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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