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Article

Minimum Effective Dose of Cattle and Sheep BSE for Oral Sheep Infection.

PloS one - 1 Jan 2016

McGovern Gillian, Martin Stuart, Jeffrey Martin, Dexter Glenda, Hawkins Steve A C, Bellworthy Sue J, Thurston Lisa, Algar Lynne, González Lorenzo

Abstract excerpt

The minimum dose required to cause infection of Romney and Suffolk sheep of the ARQ/ARQ or ARQ/ARR prion protein gene genotypes following oral inoculation with Romney or Suffolk a sheep Bovine spongiform encephalopathy (BSE)-derived or cattle BSE-derived agent was investigated using doses ranging from 0.0005g to 5g. ARQ/ARQ sheep which were methionine (M) / threonine (T) heterozygous or T/T homozygous at codon...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26968011
DOI: 10.1371/journal.pone.0151440
PMCID: PMC4788145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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