Article
Dic(17;18)(p11.2;p11.2) is a recurring abnormality in chronic lymphocytic leukaemia associated with aggressive disease.
British journal of haematology - 1 Mar 2010
Woyach Jennifer A, Heerema Nyla A, Zhao John, McFaddin Andrew, Stark Amy, Lin Thomas S, Andritsos Leslie A, Blum Kristie A, Flynn Joseph M, Jones Jeffrey A, Byrd John C
Abstract excerpt
Interphase cytogenetics are commonly used to identify clonal abnormalities in chronic lymphocytic leukemia (CLL) patients but fail to identify recurrent translocations that ultimately can direct more focused molecular characterization. Given the importance of del(17p13.1) in CLL outcome, we perfo...
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