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Article

[Aging or tumor: the crosstalk between telomerase and p53].

Yi chuan = Hereditas - 1 May 2009

Zhang Xiu-Feng, Tang Wen-Ru, Luo Ying

Abstract excerpt

Telomerase and p53 play critical roles in tumorigenesis and senescence. The mutation of p53 gene and the reactivation of telomerase have been found in most of the human tumors. Aiming telomerase and p53 genes have become important strategies in tumor therapy. We reviewed the aging and tumor phenotype in different status of telomerase and p53 (mTR/p53+/+; mTR/P53/), which indicated that telomere dysfunction could...

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Source

Identifiers

PMID: 19586837
DOI: 10.3724/sp.j.1005.2009.00451

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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