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Article

Familial aggregation of a disease consequent upon correlation between relatives in a risk factor measured on a continuous scale.

American journal of epidemiology - 1 Nov 1992

Hopper J L, Carlin J B

Abstract excerpt

Correlation between relatives in one or more risk factors for a disease will contribute to the risk in relatives of an affected individual, irrespective of the cause(s) of the correlation. In this paper, a model is proposed to quantify the relation between 1) the correlation (rho) between a random pair of relatives in a quantitative risk factor, 2) the dependence of the probability of being affected on a risk...

Topics

Breast Neoplasms
Diet
Female
Genetic Predisposition to Disease
Humans
Logistic Models
Mathematical Computing
Models, Statistical
Odds Ratio
Probability
Risk Factors

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Identifiers

PMID: 1462973
DOI: 10.1093/oxfordjournals.aje.a116580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1462973-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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