Article
Relative risks and effective number of meioses: a unified approach for general genetic models and phenotypes.
Annals of human genetics - 1 Nov 2006
Kurbasic A, Hössjer O
Abstract excerpt
Many common diseases are known to have genetic components, but since they are non-Mendelian, i.e. a large number of genetic factors affect the phenotype, these components are difficult to localize. These traits are often called complex and analysis of siblings is a valuable tool for mapping them. It has been shown that the power of the affected relative pairs method to detect linkage of a disease susceptibility...
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