Article
Multiallelic models of genetic effects and variance decomposition in non-equilibrium populations.
Genetica - 1 Sept 2011
Álvarez-Castro José M, Yang Rong-Cai
Abstract excerpt
Quantitative genetics stems from the theoretical models of genetic effects, which are re-parameterizations of the genotypic values into parameters of biological (genetic) relevance. Different formulations of genetic effects are adequate to address different subjects. We thus need to generalize and unify them under a common framework for enabling researchers to easily transform genetic effects between different...
Topics
- Alleles
- Genotype
- Humans
- Linkage Disequilibrium
- Models, Genetic
- Polymorphism, Genetic
- Protein Tyrosine Phosphatases
- Proto-Oncogene Proteins
- Quantitative Trait Loci