Article
HLA-G 3' UTR haplotypes and HIV vertical transmission.
AIDS (London, England) - 10 Sept 2009
Segat Ludovica, Catamo Eulalia, Fabris Annalisa, Padovan Lara, Morgutti Marcello, Crovella Sergio
Abstract excerpt
We evaluated the possible association of human leukocyte antigen-G (HLA-G) 3777G>C and 14-bp deletion/insertion (D/I) polymorphisms haplotypes and combined genotypes with perinatal HIV transmission in Brazilian children. The 3777G>C polymorphism alone has no effect on HIV vertical transmission but, when linked with the D allele, exerts a positive role in the protection. Indeed, we identified the DC HLA-G...
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