Article
Fetal ERAP2 variation is associated with preeclampsia in African Americans in a case-control study.
BMC medical genetics - 11 May 2011
Hill Lori D, Hilliard DaShaunda D, York Timothy P, Srinivas Sindhu, Kusanovic Juan P, Gomez Ricardo, Elovitz Michal A, Romero Roberto, Strauss Jerome F
Abstract excerpt
BACKGROUND: Preeclampsia affects 3-8% of pregnancies and is a major cause of maternal and perinatal morbidity and mortality worldwide. This complex disorder is characterized by alterations in the immune and vascular systems and involves multiple organs. There is strong evidence for a genetic contribution to preeclampsia. Two different single nucleotide polymorphisms (SNPs) in the endoplasmic reticulum...
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