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Article

The influence of genetic and environmental factors on plasma homocysteine concentrations in a population at high risk for coronary artery disease.

Annals of clinical biochemistry - 1 Nov 2005

Bowron Ann, Scott Jeff, Stansbie David

Abstract excerpt

BACKGROUND: Elevated plasma total homocysteine (tHcy) predisposes to vascular disease and results from interactions between genetic and nutritional factors. MTHFR C(677)T increases tHcy in association with low folate. CBS 844ins68 lowers tHcy and negates the raising effect of MTHFR C(677)T in healthy subjects, but it is unclear if this is the case in subjects at high risk of vascular disease. This study examines...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16259797
DOI: 10.1258/000456305774538256

Genes

MTHFR
CBS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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