Article
Association of TERT, OGG1, and CHRNA5 Polymorphisms and the Predisposition to Lung Cancer in Eastern Algeria.
Pulmonary medicine - 1 Jan 2020
Mimouni Asma, Rouleau Etienne, Saulnier Patrick, Marouani Amina, Abdelali Med Lamine, Filali Taha, Beddar Leila, Lakehal Abdelhak, Hireche Ahmed, Boudersa Asma, Aissaoui Mahmoud, Ramtani Hacene, Bouhedjar Khalid, Abdellouche Djamel, Oudjehih Messaouda, Boudokhane Ibtissem, Abadi Noureddine, Satta Dalila
Abstract excerpt
Lung cancer remains the most common cancer in the world. The genetic polymorphisms (rs2853669 in TERT, rs1052133 in OGG1, and rs16969968 in CHRNA5 genes) were shown to be strongly associated with the risk of lung cancer. Our study's aim is to elucidate whether these polymorphisms predispose Eastern Algerian population to non-small-cell lung cancer (NSCLC). To date, no study has considered this association in the...
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