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Article

A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies.

Virology - 15 Aug 2009

Torimiro Judith N, Javanbakht Hassan, Diaz-Griffero Felipe, Kim Jonghwa, Carr Jean K, Carrington Mary, Sawitzke Julie, Burke Donald S, Wolfe Nathan D, Dean Michael, Sodroski Joseph

Abstract excerpt

The global acquired immunodeficiency syndrome (AIDS) pandemic is thought to have arisen by the transmission of human immunodeficiency virus (HIV-1)-like viruses from chimpanzees in southeastern Cameroon to humans. TRIM5alpha is a restriction factor that can decrease the susceptibility of cells of particular mammalian species to retrovirus infection. A survey of TRIM5 genes in 127 indigenous individuals from...

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Source

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Identifiers

PMID: 19577266
DOI: 10.1016/j.virol.2009.05.038
PMCID: PMC2760473

Genes

TRIM5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies.PMID 19577266Read ↗

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