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Article

Double-blind crossover study of the cognitive effects of lorazepam in healthy apolipoprotein E (APOE)-epsilon4 carriers.

The Journal of clinical psychiatry - 1 Oct 2009

Stonnington Cynthia M, Snyder Peter J, Hentz Joseph G, Reiman Eric M, Caselli Richard J

Abstract excerpt

OBJECTIVE: To examine cognitive effects of pharmacologically induced somnolence in cognitively normal carriers and noncarriers of the apolipoprotein E (APOE)-epsilon4 allele, a common Alzheimer's disease susceptibility gene. METHOD: Between December 2005 and July 2007, healthy and cognitively normal carriers of the APOE-epsilon4 allele (heterozygotes; n = 18) and noncarriers (n = 18), 50 to 65 years old,...

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Source

Identifiers

PMID: 19573495
DOI: 10.4088/JCP.08m04593

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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