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Article

Apolipoprotein E epsilon4 allele and lorazepam effects on memory in high-functioning older adults.

Archives of general psychiatry - 1 Feb 2005

Pomara Nunzio, Willoughby Lisa, Wesnes Keith, Greenblatt David J, Sidtis John J

Abstract excerpt

CONTEXT: The apolipoprotein E (APOE) epsilon4 allele has been implicated as a significant risk factor in the development of late-onset Alzheimer disease, but the evidence of cognitive sequelae in healthy individuals has been mixed. OBJECTIVE: To determine if the APOE epsilon4 allele increases susceptibility to lorazepam-induced verbal learning impairment in nondemented older adults. DESIGN: A placebo-controlled...

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Source

Identifiers

PMID: 15699298
DOI: 10.1001/archpsyc.62.2.209

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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