Article
A distinctive interaction between memory and chronic daytime somnolence in asymptomatic APOE e4 homozygotes.
Sleep - 15 Jun 2002
Caselli Richard J, Reiman Eric M, Hentz Joseph G, Osborne David, Alexander Gene E, Boeve Bradley F
Abstract excerpt
STUDY OBJECTIVES: To correlate memory measures with a trait measure of chronic daytime somnolence in cognitively normal individuals with different gene doses of the apolipoprotein E (APOE) e4 allele, a common Alzheimer's disease susceptibility gene. DESIGN: Cross-sectional, exploratory study of cognitive abilities in APOE e4 homozygotes (HMZ) (n=42), heterozygotes (HTZ), (n=42) and noncarriers (NC) (n=42) who are...
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