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Article

Nuclear envelope morphology constrains diffusion and promotes asymmetric protein segregation in closed mitosis.

The Journal of cell biology - 25 Jun 2012

Boettcher Barbara, Marquez-Lago Tatiana T, Bayer Mathias, Weiss Eric L, Barral Yves

Abstract excerpt

During vegetative growth, Saccharomyces cerevisiae cells divide asymmetrically: the mother cell buds to produce a smaller daughter cell. This daughter asymmetrically inherits the transcription factor Ace2, which activates daughter-specific transcriptional programs. In this paper, we investigate when and how this asymmetry is established and maintained. We show that Ace2 asymmetry is initiated in the elongated,...

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Identifiers

PMID: 22711697
DOI: 10.1083/jcb.201112117
PMCID: PMC3384416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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