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Article

Genetic variation at the TNF-alpha promoter and malaria susceptibility in rhesus (Macaca mulatta) and long-tailed (Macaca fascicularis) macaques.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2009

Flynn Shannon, Satkoski Jessica, Lerche Nicholas, Kanthaswamy Sreetharan, Smith David Glenn

Abstract excerpt

Polymorphisms within the promoter region of the TNF-alpha gene have been associated with altered expression of TNF-alpha and susceptibility to a variety of diseases in humans. Although macaques (Macaca spp.) are frequently used as models to study human diseases, little is known about the extent of genetic variation at the TNF-alpha locus and its consequences for disease susceptibility in these species. The...

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Source

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PMID: 19570728
DOI: 10.1016/j.meegid.2009.03.011

Genes

TNF
FST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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