Low genetic diversity of major histocompatibility complex class II DQB gene in wild rhesus and long-tailed macaques in Thailand reflects purifying selection and poses risks to population health.

Abstract excerpt

Rhesus (Macaca mulatta) and long-tailed (M. fascicularis) macaques, important for biomedical research, are distributed across Thailand, and hybridization and introgression between species influence genetic diversity, potentially leading to variability in traits and pathogen susceptibility. Elucidation of the genetic components directly related to pathogen susceptibility, such as major histocompatibility complex...

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