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Control freaks—signals and cues governing the regulation of virulence in attaching and effacing pathogens

17 Dec 2018

Abstract excerpt

(EHEC) mediates disease using a type 3 secretion system (T3SS), which is encoded on the locus of enterocyte effacement (LEE) and is tightly controlled by master regulators. This system is further modulated by a number of signals that help to fine-tune virulence, including metabolic, environmental and chemical signals. Since the LEE and its master regulator, Ler, were established, there have been numerous...

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PMID: 30559275
DOI: 10.1042/bst20180546

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