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Article

Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis.

Environmental health perspectives - 1 Nov 1992

Kadlubar F F, Butler M A, Kaderlik K R, Chou H C, Lang N P

Abstract excerpt

The metabolic pathways associated with carcinogenic aromatic amines in humans provide an excellent example of polymorphisms that appear to be relevant to human carcinogenesis. In this regard, the N-acetylation of arylamines and the O-acetylation of their N-hydroxy metabolites are catalyzed preferentially by a genetically polymorphic acetyltransferase, high activity of which has been correlated with decreased risk...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 1486865
DOI: 10.1289/ehp.929869
PMCID: PMC1519630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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