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Article

NRN1 genetic variability and methylation changes as biomarkers for cognitive remediation therapy response in schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2025

Almodóvar-Payá Carmen, París-Gómez Irene, Latorre-Guardia Mariona, Guardiola-Ripoll Maria, Catalán Rosa, Arias Bárbara, Penadés Rafael, Fatjó-Vilas Mar

Abstract excerpt

Cognitive remediation therapy (CRT) demonstrates potential in enhancing cognitive function in schizophrenia (SZ), though the identification of molecular biomarkers remains challenging. The Neuritin-1 gene (NRN1) emerges as a promising candidate gene due to its association with SZ, cognitive performance and response to neurotherapeutic treatments. We aimed to investigate whether NRN1 genetic variability and...

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Identifiers

PMID: 39426559
DOI: 10.1016/j.pnpbp.2024.111175

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NRN1

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