Article
Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.
The British journal of psychiatry : the journal of mental science - 1 Jul 2009
Hamshere M L, Green E K, Jones I R, Jones L, Moskvina V, Kirov G, Grozeva D, Nikolov I, Vukcevic D, Caesar S, Gordon-Smith K, Fraser C, Russell E, Breen G, St Clair D, Collier D A, Young A H, Ferrier I N, Farmer A, McGuffin P, Holmans P A, Owen M J, O'Donovan M C, Craddock N
Abstract excerpt
BACKGROUND: Psychiatric phenotypes are currently defined according to sets of descriptive criteria. Although many of these phenotypes are heritable, it would be useful to know whether any of the various diagnostic categories in current use identify cases that are particularly helpful for biological-genetic research. AIMS: To use genome-wide genetic association data to explore the relative genetic utility of seven...
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