Article
Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder.
Schizophrenia bulletin - 1 May 2014
Cardno Alastair G, Owen Michael J
Abstract excerpt
There is substantial evidence for partial overlap of genetic influences on schizophrenia and bipolar disorder, with family, twin, and adoption studies showing a genetic correlation between the disorders of around 0.6. Results of genome-wide association studies are consistent with commonly occurring genetic risk variants, contributing to both the shared and nonshared aspects, while studies of large, rare...
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