Article
Relation of polymorphism within the C-reactive protein gene and plasma CRP levels.
Atherosclerosis - 1 Jan 2005
Suk H Jacqueline, Ridker Paul M, Cook Nancy R, Zee Robert Y L
Abstract excerpt
We sought to investigate whether genetic variability within the CRP gene affects CRP levels. C-reactive protein (CRP), an acute-phase reactant in inflammation, is an important predictor for cardiovascular disease. The genetic determinants of plasma CRP level remain unknown. We assessed the genotypes of two common polymorphisms within the CRP gene, an exonic 1059G > C and an intronic T > A base substitution, among...
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