Article
Universal translators for nucleic acid diagnosis.
Journal of the American Chemical Society - 8 Jul 2009
Picuri John M, Frezza Brian M, Ghadiri M Reza
Abstract excerpt
Defined broadly, molecular translators are constructs that can convert any designated molecular input into a unique output molecule. In particular, the development of universal nucleic acid translators would be of significant practical value in view of the expanding biomedical importance of gene diagnostics. Currently, diagnostic assays for nucleic acids must be individually developed and optimized for each new...
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