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Article

Establishment of a human neonatal hepatocyte cell line.

In vitro cellular & developmental biology. Animal - 1 Oct 2009

Reid Yvonne, Gaddipati Jaya P, Yadav Deepmala, Kantor Judy

Abstract excerpt

Hepatocytes are routinely used to generate and identify drug metabolites and hepatic toxicity. Primary cultures of human hepatocytes are the model cell of choice for most of these pharmacological and toxicological studies. However, major problems are encountered with primary liver cell cultures: the dwindling availability of viable livers, hepatocytes having a limited life span, the loss of liver-specific...

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Identifiers

PMID: 19565302
DOI: 10.1007/s11626-009-9219-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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