Association of plasma homocysteine and methylenetetrahydrofolate reductase C677T gene variant with schizophrenia: A Chinese Han population-based case-control study.

Abstract excerpt

This study examined the association of plasma homocysteine levels and the methylenetetrahydrofolate reductase (MTHFR) gene polymorphism with schizophrenia in the Han population residing in northern China. We detected the MTHFR C677T genotype in 123 schizophrenia patients and compared it with the genotype of 123 controls by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). In addition,...

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