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Plasma total homocysteine is associated with DNA methylation in patients with schizophrenia

1 Jun 2013

Abstract excerpt

Schizophrenia (SCZ) is a devastating psychiatric disorder with a median lifetime prevalence rate of 0.7-0.8%. Elevated plasma total homocysteine has been suggested as a risk factor for SCZ, and various biological effects of hyperhomocysteinemia have been proposed to be relevant to the pathophysiology of SCZ. As increased attention is paid to aberrant DNA methylation in SCZ, homocysteine is attracting additional...

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PMID: 23774737
DOI: 10.4161/epi.24621

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