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Article

The combined expression of HOXA4 and MEIS1 is an independent prognostic factor in patients with AML.

European journal of haematology - 1 Nov 2009

Zangenberg Mike, Grubach Lykke, Aggerholm Anni, Silkjaer Trine, Juhl-Christensen Caroline, Nyvold Charlotte Guldborg, Kjeldsen Eigil, Ommen Hans Beier, Hokland Peter

Abstract excerpt

HOXA4 gene expression is a predictor for outcome in normal karyotypic acute myeloid leukaemia (AML) patients. Given that Meis1 is a co-factor for Hox genes, we hypothesized that the combined expression of HOXA4 and MEIS1 might add prognostic information in these patients. When diagnostic samples from 246 AML patients were divided into three main groups based on gene expression levels of HOXA4 combined with MEIS1...

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Share to Disease-Free Survival
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Leukemia, Myeloid, Acute

Share to Myeloid Ecotropic Viral Integration Site 1 Protein

Share to Neoplasm Proteins

Share to Nucleophosmin

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Source

Identifiers

PMID: 19563517
DOI: 10.1111/j.1600-0609.2009.01309.x

Genes

HOXA4
MEIS1
NPM1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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