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Article

Allelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose.

Current biology : CB - 11 Aug 2009

Fushan Alexey A, Simons Christopher T, Slack Jay P, Manichaikul Ani, Drayna Dennis

Abstract excerpt

Human sweet taste perception is mediated by the heterodimeric G protein-coupled receptor encoded by the TAS1R2 and TAS1R3 genes. Variation in these genes has been characterized, but the functional consequences of such variation for sweet perception are unknown. We found that two C/T single-nucleotide polymorphisms (SNPs) located at positions -1572 (rs307355) and -1266 (rs35744813) upstream of the TAS1R3 coding...

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Identifiers

PMID: 19559618
DOI: 10.1016/j.cub.2009.06.015
PMCID: PMC2742917

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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