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Article

ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.

Molecular endocrinology (Baltimore, Md.) - 1 Oct 2009

Kim Dae-Hwan, Lee Jeongkyung, Lee Bora, Lee Jae W

Abstract excerpt

Activating signal cointegrator-2 (ASC-2), a coactivator of multiple nuclear receptors and transcription factors, belongs to a steady-state complex named ASCOM (for ASC-2 complex), which contains histone H3 lysine 4 (H3K4) methyltransferase MLL3 or its paralog MLL4. ASC-2 binds to many nuclear rec...

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Identifiers

PMID: 19556342
DOI: 10.1210/me.2009-0099
PMCID: PMC2754897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19556342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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