Article
An association study of 22 candidate genes in psoriasis families reveals shared genetic factors with other autoimmune and skin disorders.
The Journal of investigative dermatology - 1 Nov 2009
Oudot Tiphaine, Lesueur Fabienne, Guedj Mickaël, de Cid Rafael, McGinn Steven, Heath Simon, Foglio Mario, Prum Bernard, Lathrop Mark, Prud'homme Jean-François, Fischer Judith
Abstract excerpt
Psoriasis is a common inflammatory and hyperproliferative skin disease. Recent studies have reported that common genetic factors may underlie both skin and immune-mediated disorders. We hypothesized that such genes may be involved in susceptibility to psoriasis, and undertook an association analysis of 22 candidate genes in a set of French high-risk psoriasis families. One hundred fifty-three single-nucleotide...
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