Article
A transcriptome-wide association study identifies novel susceptibility genes for psoriasis.
Human molecular genetics - 27 Dec 2021
Zhu Dongli, Yao Shi, Wu Hao, Ke Xin, Zhou Xiaorong, Geng Songmei, Dong Shanshan, Chen Hao, Yang Tielin, Cheng Ying, Guo Yan
Abstract excerpt
Although >80 psoriasis genetic risk loci have been reported through genome-wide association studies (GWASs), the genetic mechanism of psoriasis remains unclear. To identify novel candidate genes associated with psoriasis and reveal the potential effects of genetic factors in the development of psoriasis, we conducted a transcriptome-wide association study (TWAS) based on summary statistics from GWAS of psoriasis...
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