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Article

Distinct expression profiles and functions of Kindlins in breast cancer

26 Nov 2018

Abstract excerpt

BACKGROUND: Kindlin-1, - 2, and - 3 are the three members of the Kindlin family. They are best known as regulators of integrin functions, contributing to fundamental biological processes such as cell survival, adhesion and migration. Their deregulation leads to diverse pathologies including a broad range of cancers in which both, tumor-promoting and tumor-inhibiting functions have been described. METHODS: To...

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PMID: 30477537
DOI: 10.1186/s13046-018-0955-4

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