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Article

Significant Association of Interleukin4 Intron 3 VNTR Polymorphism with Susceptibility to Gastric Cancer in a South Indian Population from Telangana.

PloS one - 1 Jan 2015

Bhayal Amar Chand, Krishnaveni Devulapalli, Rao Kondadasula Pandu Ranga, Kumar Adi Rakesh, Jyothy Akka, Nallari Pratibha, Venkateshwari Ananthapur

Abstract excerpt

BACKGROUND: Gastric cancer (GC) is the fifth most common malignancy and remains a considerable public health burden worldwide. Genetic variations in genes encoding cytokines and their receptors influence the intensity of the Helicobacter pylori associated inflammatory response, which may contribute to individual differences in the outcome and severity of the disease. Interleukin4 is a typical pleiotropic T helper...

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PMID: 26383107
DOI: 10.1371/journal.pone.0138442
PMCID: PMC4575215

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