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Article

Novel mutations in GP IIb gene in Glanzmann's thrombasthenia from India.

Platelets - 1 Feb 2009

Vijapurkar Manasi, Ghosh Kanjaksha, Shetty Shrimati

Abstract excerpt

The integrin GPIIb-IIIa plays an important role in platelet activation and plug formation. Quantitative and qualitative dysfunction in this receptor causes Glanzmann's thrombasthenia (GT) and leads to a bleeding tendency. Mutations in the GPIIb or GPIIIa gene are known to be responsible for the inherited form of this disease, which is characterized by mucocutaneous bleeding and other clinically severe bleeding...

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PMID: 19172520
DOI: 10.1080/09537100802434861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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