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Article

CYP3A5 *1 allele: impacts on early acute rejection and graft function in tacrolimus-based renal transplant recipients.

Transplantation - 27 Dec 2010

Min Sang-Il, Kim Seong Yup, Ahn Sang Hyun, Min Seung-Kee, Kim Si Hwa, Kim Yon Su, Moon Kyung Chul, Oh Jung Mi, Kim Sang Joon, Ha Jongwon

Abstract excerpt

BACKGROUND: Tacrolimus is a major immunosuppressant, which has a narrow therapeutic range and wide interindividual variation. The effects of genetic polymorphisms of cytochrome P450 3A (CYP3A) 5 and Adenosine triphosphate-binding cassette subfamily B member 1 (ABCB1) genes on the achievement of target tacrolimus trough levels and clinical outcomes in renal transplants were evaluated. METHODS: A total of 62...

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ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1
Cytochrome P-450 CYP3A
Graft Rejection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunosuppressive Agents

Patient Selection

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Identifiers

PMID: 21076384
DOI: 10.1097/TP.0b013e3181fa93a4

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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CYP3A5 *1 allele: impacts on early acute rejection and graft function in tacrolimus-based renal transplant recipients.PMID 21076384Read ↗

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