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Article

Dual excitatory and inhibitory serotonergic inputs modulate egg laying in Caenorhabditis elegans.

Genetics - 1 Jan 2009

Hapiak Vera M, Hobson Robert J, Hughes Lindsay, Smith Katherine, Harris Gareth, Condon Christina, Komuniecki Patricia, Komuniecki Richard W

Abstract excerpt

Serotonin (5-HT) regulates key processes in both vertebrates and invertebrates. Previously, four 5-HT receptors that contributed to the 5-HT modulation of egg laying were identified in Caenorhabditis elegans. Therefore, to assess potential receptor interactions, we generated animals containing combinations of null alleles for each receptor, especially animals expressing only individual 5-HT receptors....

Topics

Amino Acid Sequence
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Female
Locomotion
Models, Biological
Molecular Sequence Data
Muscles
Mutation
Oviposition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phylogeny

Receptors, Serotonin

Serotonin

Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 19001289
DOI: 10.1534/genetics.108.096891
PMCID: PMC2621164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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