Article
Dual excitatory and inhibitory serotonergic inputs modulate egg laying in Caenorhabditis elegans.
Genetics - 1 Jan 2009
Hapiak Vera M, Hobson Robert J, Hughes Lindsay, Smith Katherine, Harris Gareth, Condon Christina, Komuniecki Patricia, Komuniecki Richard W
Abstract excerpt
Serotonin (5-HT) regulates key processes in both vertebrates and invertebrates. Previously, four 5-HT receptors that contributed to the 5-HT modulation of egg laying were identified in Caenorhabditis elegans. Therefore, to assess potential receptor interactions, we generated animals containing combinations of null alleles for each receptor, especially animals expressing only individual 5-HT receptors....
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