Article
Confirmed non-invasive prenatal testing for foetal Rh blood group genotyping along with bi-allelic short insertion/deletion polymorphisms as a positive internal control.
Transfusion medicine (Oxford, England) - 1 Apr 2022
Armstrong-Fisher Sylvia, Koushki Khadijeh, Mashayekhi Kazem, Urbaniak Stanislaw J, van der Schoot Ellen, Varzi Ali Mohammad
Abstract excerpt
BACKGROUND: Determination of foetus rhesus blood group at risk of hemolytic disease has potential application for early non-invasive prenatal testing (NIPT). There are several challenges in developing NIPT rhesus blood group genotyping assays by using cell-free foetal DNA (cff-DNA) in plasma of RhD-negative pregnant women. So, the aim of this study was optimization of Real-time PCR assay for NIPT rhesus...
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