Article
Chromosome 3p microsatellite allelotyping in neuroblastoma: a report on the technical hurdles.
Cancer investigation - 1 Oct 2009
Hoebeeck Jasmien, De Wilde Bram, Michels Evi, Combaret Valérie, Yigit Nurten, De Smet Els, Van Roy Nadine, Stanbridge Eric, Ru Ning, Laureys Geneviève, De Paepe Anne, Speleman Frank, Vandesompele Jo
Abstract excerpt
Pinpointing critical regions of recurrent loss may help localize tumor suppressor genes. To determine the regions of loss on chromosome 3p in neuroblastoma, we performed loss of heterozygosity analysis using 16 microsatellite markers in a series of 65 primary tumors and 29 neuroblastoma cell lines. In this study, we report the results and discuss the technical hurdles that we encountered during data generation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
