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Article

Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal melanoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 May 2007

Onken Michael D, Worley Lori A, Person Erica, Char Devron H, Bowcock Anne M, Harbour J William

Abstract excerpt

PURPOSE: Loss of chromosome 3 is strongly associated with metastasis in uveal melanoma and has been proposed as the basis for clinical prognostic testing. It is not known whether techniques that identify loss of heterozygosity for chromosome 3 predict metastasis more accurately than those that detect only numerical loss of chromosome 3 (monosomy 3). EXPERIMENTAL DESIGN: Fifty-three uveal melanomas were analyzed...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Source

Identifiers

PMID: 17504992
DOI: 10.1158/1078-0432.CCR-06-2383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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