Article
Non-association between polymorphisms of the frizzled receptor genes and bone mineral density in postmenopausal Korean women.
Journal of Korean medical science - 1 Jun 2009
Kim Jung Gu, Kim Hoon, Jee Byung Chul, Suh Chang Suk, Choi Young Min, Moon Shin Yong
Abstract excerpt
We investigated the association between single nucleotide polymorphisms (SNPs) in the frizzled (FZD) genes in the Wnt signal pathway and circulating osteoprotegerin (OPG), soluble receptor activator of NF-kappaB ligand (sRANKL) levels, bone turnover markers, and bone mineral density (BMD) in postmenopausal women. The SNPs in the FZD1, FZD5, FZD6, FZD7, and FZD9 genes were analyzed by direct sequencing in 371...
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