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Article

HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients.

Clinical journal of the American Society of Nephrology : CJASN - 1 Aug 2009

Valenti Luca, Girelli Domenico, Valenti Giovanni Francesco, Castagna Annalisa, Como Giovanna, Campostrini Natascia, Rametta Raffaela, Dongiovanni Paola, Messa Piergiorgio, Fargion Silvia

Abstract excerpt

BACKGROUND AND OBJECTIVES: Increased serum hepcidin has been reported in patients receiving chronic hemodialysis, and hypothesized to contribute to the alterations of iron metabolism of end-stage renal disease. However, no quantitative assessment is available to date; the clinical determinants are still under definition; and the role of genetic factors, namely HFE mutations, has not yet been evaluated. The aim of...

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Share to Anemia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19541813
DOI: 10.2215/CJN.01370209
PMCID: PMC2723967

Genes

HFE
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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