HFE mutations and iron in hemodialysis patients.

Abstract excerpt

In chronic hemodialysis patients, a disruption in iron metabolism ranging from absolute to functional deficiency, with compartmentalization of this metal into macrophages, is often observed. Chronic inflammation indeed often causes an upregulation of the iron hormone hepcidin, thereby reducing iron absorption and availability to the erythron. We systematically reviewed the literature on the role of genetic risk...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to HFE gene
• Share to TMPRSS6 gene
• Share to Hemochromatosis Protein