Article
Hemochromatosis gene mutations and treatment of anemia in patients on hemodialysis.
Hemodialysis international. International Symposium on Home Hemodialysis - 1 Oct 2009
Brown Michaela C, Gaffney Dairena, Gemmell Clare, Oakes Eleanor, Morris Scott, Spooner Richard, Jardine Alan G, Geddes Colin C
Abstract excerpt
Hemochromatosis causes iron overload by enhanced intestinal absorption. This study examined erythropoietin and intravenous (i.v.) iron requirements in hemodialysis (HD) patients with HFE mutations. Patients on HD for > 90 days with no cause of anemia except chronic kidney disease were tested for HFE mutations (H63D and C282Y). Intravenous iron and erythropoietin doses were adjusted to achieve recommended targets....
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