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Article

HFE gene mutations and oxidative stress influence serum ferritin, associated with vascular damage, in hemodialysis patients.

American journal of nephrology - 1 Jan 2007

Valenti Luca, Valenti Gianfranco, Como Giovanna, Burdick Larry, Santorelli Gennaro, Dongiovanni Paola, Rametta Raffaela, Bamonti Fabrizia, Novembrino Cristina, Fracanzani Anna Ludovica, Messa Pier Giorgio, Fargion Silvia

Abstract excerpt

BACKGROUND/AIMS: Hyperferritinemia has been associated with cardiovascular mortality in hemodialysis patients. The aim of this study was to evaluate whether serum ferritin was affected by iron and oxidative status and by genetic factors (HFE mutations and the Ala9Val MnSOD polymorphism), and to assess the association between ferritin and cardiovascular damage evaluated by ecocolor-Doppler. METHODS: 63...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17299255
DOI: 10.1159/000099635

Genes

HFE

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