Article
HFE genotype influences erythropoiesis support requirement in hemodialysis patients: a prospective study.
American journal of nephrology - 1 Jan 2008
Valenti Luca, Valenti Giovanni, Como Giovanna, Santorelli Gennaro, Dongiovanni Paola, Rametta Raffaela, Fracanzani Anna Ludovica, Tavazzi Dario, Messa Pier Giorgio, Fargion Silvia
Abstract excerpt
BACKGROUND/AIMS: HFE protein controls iron absorption and cycling, and HFE mutations influence iron status. The aim was to evaluate the effect of the HFE genotype on the need for iron and erythropoietin in Italian hemodialysis patients. METHODS: Ninety-six prevalent patients were evaluated at the time of enrolment and prospectively followed for 3 years. Patients were given r-HuEPO and Fe3+-gluconate according to...
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