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Article

Regulation of protein activity with small-molecule-controlled inteins.

Protein science : a publication of the Protein Society - 1 Feb 2005

Skretas Georgios, Wood David W

Abstract excerpt

Inteins are the protein analogs of self-splicing RNA introns, as they post-translationally excise themselves from a variety of protein hosts. Intein insertion abolishes, in general, the activity of its host protein, which is subsequently restored upon intein excision. These protein elements therefore have the potential to be used as general molecular "switches" for the control of arbitrary target proteins. Based...

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Identifiers

PMID: 15632292
DOI: 10.1110/ps.04996905
PMCID: PMC2386410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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