Article
Nuclear factor I regulates brain fatty acid-binding protein and glial fibrillary acidic protein gene expression in malignant glioma cell lines.
Journal of molecular biology - 14 Aug 2009
Brun Miranda, Coles Jeffrey E, Monckton Elizabeth A, Glubrecht Darryl D, Bisgrove Dwayne, Godbout Roseline
Abstract excerpt
Glial fibrillary acidic protein (GFAP), an intermediate filament protein normally found in astrocytes, and the radial glial marker brain fatty acid-binding protein (B-FABP; also known as FABP7) are co-expressed in malignant glioma cell lines and tumors. Nuclear factor I (NFI) recognition sites have been identified in the B-FABP and GFAP promoters, and transcription of both genes is believed to be regulated by...
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